Evidence from urinary cortisol that maternal behavior is related to stress in gorillas
Evidence from urinary cortisol that maternal behavior is related to stress in gorillas
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DOI：
10.1016/s0031-9384(98)00057-2
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发表时间：
1998-06-15
影响因子：
2.9
通讯作者：
Martin, RD
中科院分区：
文献类型：
--
作者：
Bahr, NI;Pryce, CR;Martin, RD
通过行为学和非侵入性生理学技术对动物园中的西部低地大猩猩（Gorilla gorilla gorilla，n = 8）进行研究，我们证明了它们的产后母性行为与其产后尿皮质醇滴度呈负相关。基于这一发现，有人提出，产后压力有助于破坏圈养大猩猩的母性行为。从产后第14天至产后第14天，以平均1.6天的采样间隔采集早晨尿液样本（n = 11例妊娠）。肌酐指数（Cr）尿皮质醇滴度在产后第9天至第1天（0.634 +/- 0.014 μ g/mg Cr，平均值+/- SEM）和产后第1天至第6天（0.396 +/- 0.030 μ g/mg Cr，平均值+/- SEM; p < 0.01-0.001）显著下降。对于每次妊娠，尿皮质醇的相对产后下降计算为（第1 - 4天皮质醇μ g/mg Cr）/（第-4天至-1天皮质醇μ g/mg Cr）。值范围为0.35至1.12，是独立的绝对肾上腺皮质醇滴度，并解释为产后下丘脑-垂体-肾上腺轴活动，因此，产后压力的女性间差异的证据。该产后应激指数与女性在运动期间以腹侧位置携带和支撑其0-14天大的婴儿的时间量（0-100%）呈负相关（r（s）=-0.68，P < 0.05），并与他们与婴儿腹-腹接触的总时间（0-100%）呈负相关（r（s）= -0.58; p < 0.10）。这项研究提供了第一个生理证据，产后压力是一个重要的病因因素，在圈养环境中的大猩猩母性失败。(C)1998年爱思唯尔科学公司
By studying western lowland gorillas (Gorilla gorilla gorilla, n = 8) in zoological gardens via ethological and non-invasive physiological techniques, we have demonstrated that their postpartum maternal behavior is related negatively to their postpartum urinary titers of cortisol. On the basis of this finding, it is proposed that postpartum stress contributes to disrupted maternal behavior in the gorilla in captivity. Morning urine samples were collected with a mean sampling interval of 1.6 days from Day 14 prepartum to Day 14 postpartum (n = 11 pregnancies). Creatinine-indexed (Cr) urinary cortisol titers declined significantly between Day 9 to 1 prepartum (0.634 +/- 0.014 mu g/mg of Cr, mean +/- SEM) and Day 1 to 6 postpartum (0.396 +/- 0.030 mu g/mg of Cr, mean +/- SEM; p < 0.01-0.001). For each pregnancy, the relative postpartum decline in urinary cortisol was calculated as (mu g of cortisol/mg of Cr Day 1 to 4)/(mu g of cortisol/mg of Cr Day -4 to -1). Values ranged from 0.35 to 1.12, were independent of absolute prepartum cortisol titers, and were interpreted as evidence of inter-female differences in postpartum hypothalamo-pituitary-adrenal axis activity and, therefore, postpartum stress. This postpartum stress index was negatively correlated with the amount of time (0-100%) that females carried and supported their 0-14 day-old infants in a ventral position during locomotion (r(s) = -0.68, p < 0.05) and tended to be negatively correlated with the total amount of time (0-100%) they spent in ventro-ventral contact with their infants (r(s) = -0.58; p < 0.10). This study provides the first physiological evidence that postpartum stress is an important etiologic factor in gorilla maternal failure in captive environments. (C) 1998 Elsevier Science Inc.