INHIBITION OF CENTRAL VESTIBULAR NEURONS FROM CONTRALATERAL LABYRINTH AND ITS MEDIATING PATHWAY
INHIBITION OF CENTRAL VESTIBULAR NEURONS FROM CONTRALATERAL LABYRINTH AND ITS MEDIATING PATHWAY
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DOI：
10.1152/jn.1966.29.3.467
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发表时间：
1966-01-01
影响因子：
2.5
通讯作者：
PRECHT, W
中科院分区：
文献类型：
--
作者：
SHIMAZU, H;PRECHT, W
用微电极技术记录了失脑、未麻醉猫前庭核的场电位和单个神经元放电。每个前庭神经元通过其对水平角加速度的反应来识别。前庭神经的单次电击在对侧前庭核的腹内侧部分诱发正负场电位。正向高峰延迟时间为2.5毫秒。沿中线切开脑干背侧部分后，这种电位消失。对侧前庭神经刺激可使H型神经元兴奋，最短潜伏期为3.2 msec。I型神经元被对侧前庭神经弱刺激抑制，潜伏期为4.0 msec。这种抑制被上述脑干背部中线切口所消除，取而代之的是更强刺激的兴奋性反应。提示部分II型神经元为插层抑制神经元，通过互交纤维激活，抑制同侧I型神经元。
Field potentials and single neuronal discharges in the vestibular nuclei were recorded with microelectrode technique in the decerebrate, unanesthetized cats. Each vestibular neuron was identified by its responses to horizontal angular accelerations. Single shock of the vestibular nerve induced positive-negative field potentials in the ventro-medial part of the contralateral vestibular nuclei. The latency of the positive summit was 2.5 msec. This potential was abolished after incising the dorsal part of the brain stem along the midline. Type H neurons were excited by stimulation of the contralateral vestibular nerve, the shortest latency being 3.2 msec. Type I neurons were inhibited by weak stimulation of the contralateral vestibular nerve with a latency of 4.0 msec. This inhibition was abolished by the above mentioned midline incision of the dorsal brain stem and replaced by excitatory responses with stronger stimulation. It was suggested that some of type II neurons are intercalated inhibitory neurons which are activated through commissural fibers and inhibit ipsilateral type I neurons.