Dietary Patterns and Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study
Dietary Patterns and Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study
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DOI：
10.1093/gerona/glw117
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发表时间：
2016-10-01
影响因子：
5.1
通讯作者：
Tsuji, Ichiro
中科院分区：
文献类型：
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作者：
Tomata, Yasutake;Sugiyama, Kemmyo;Tsuji, Ichiro
虽然有人推测日本的饮食模式对痴呆症有预防作用，但还没有研究报告调查这个问题。本前瞻性队列研究调查了日本老年人的饮食模式和痴呆事件之间的关系。我们分析了14，402名老年人（每千日元65岁的部分）参与社区前瞻性队列研究的5.7年随访数据。三种饮食模式（日本模式，动物性食物模式，和高乳制品模式），使用主成分分析的39个食品和饮料项目的消费，使用食品频率问卷进行评估。从公共长期护理保险数据库中检索痴呆症发病数据，随访71,043人年，痴呆症发病率为9.0%。日本饮食模式的评分与痴呆症发病风险较低相关（最高四分位数与最低四分位数的风险比为0.80; 95%置信区间：0.66-0.97; p趋势= 0.016）。动物性食物模式和高乳制品模式与痴呆症发病率无显著相关性。在日本老年人中，日本饮食模式与痴呆症发病率降低相关。
Although it has been speculated that the Japanese dietary pattern has a preventive effect against incident dementia, no reported study has yet investigated this issue. The present prospective cohort study investigated the association between dietary patterns and incident dementia in elderly Japanese subjects.We analyzed follow-up data covering a 5.7-year period for 14,402 older adults (a parts per thousand yen65 years) participating in a community-based, prospective cohort study. Three dietary patterns (Japanese pattern, animal food pattern, and high-dairy pattern) were derived using principal component analysis of the consumption of 39 food and beverage items assessed using a food frequency questionnaire. Data on incident dementia were retrieved from the public Long-term Care Insurance database.With 71,043 person-years of follow-up, incidence of dementia was 9.0%. The score for the Japanese dietary pattern was associated with a lower risk of incident dementia (hazard ratio of the highest quartile vs the lowest, 0.80; 95% confidence interval: 0.66-0.97; p-trend = .016). The animal food pattern and the high-dairy pattern showed no significant association with incident dementia.In this population of elderly Japanese individuals, the Japanese dietary pattern was associated with a decreased risk of incident dementia.