A rapid and portable sensor based on protein-modified gold nanoparticle probes and lateral flow assay for naked eye detection of mercury ion
A rapid and portable sensor based on protein-modified gold nanoparticle probes and lateral flow assay for naked eye detection of mercury ion
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DOI：
10.1016/j.mee.2012.03.015
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发表时间：
2012-09-01
影响因子：
2.3
通讯作者：
Ko, Fu-Hsiang
中科院分区：
文献类型：
--
作者：
Chao, Cheng-Han;Wu, Chung-Shu;Ko, Fu-Hsiang
几十年来，重金属离子对环境的污染一直是全球关注的重要问题。其中，汞离子（Hg2+）由于其毒性，是检测中保留的重金属离子之一。在这项研究中，我们设计了羧基修饰的蛋白质的金纳米粒子（AuNP）探针，并采用侧流法检测Hg 2+没有复杂的仪器和技术专长。在传感器的测试区和对照区上捕获的AuNP探针产生特征性的红色条带，使得能够视觉区分Hg 2+浓度。汞离子分析在环境中的应用需要平行的分析策略，这种方法简单，快速，具有巨大的应用潜力，汞离子监测在环境中，水，食品样品。(C)2012爱思唯尔有限公司版权所有。
Contamination of the environment with heavy metal ions has been an important worldwide concern for decades. Among them, mercury ion (Hg2+) is one of the heavy metal ion maintained in the detection because of its toxicity. In this study, we have designed the gold nanoparticle (AuNP) probes of carboxylic modified protein and employed the lateral flow assay to detect the Hg2+ without complicated instrumentations and technical expertise. The captured AuNP probes on the test zone and control zone of the sensor produced the characteristic red bands, enabling visual discrimination of Hg2+ concentrations. The demand of Hg2+ analysis in environmental applications requires parallel analytical strategies; such a method with simplicity and rapidity has enormous potential for the application of Hg2+ monitoring in environment, water, and food samples. (C) 2012 Elsevier B.V. All rights reserved.