PrEP Use and Correlates of Use Among a Large, Urban Sample of Men and Transgender Persons Who Have Sex with Men.
PrEP Use and Correlates of Use Among a Large, Urban Sample of Men and Transgender Persons Who Have Sex with Men.
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大量城市男性和跨性别者中男男性行为者的 PrEP 使用情况及其使用相关性。
DOI：
10.1007/s10461-021-03456-w
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发表时间：
2022
影响因子：
4.4
通讯作者：
Edelstein,ZoeR
中科院分区：
文献类型：
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作者：
Rathakrishnan,Dinesh;Purpura,LawrenceJ;Salcuni,PaulM;Myers,JulieE;Wahnich,Amanda;Daskalakis,DemetreC;Edelstein,ZoeR
我们调查了参与纽约市卫生局在 2016 年 11 月至 2017 年 1 月期间开展的家庭艾滋病毒自我检测计划的大量男男性行为者、跨性别者和性别不合格者的近期暴露前预防 (PrEP) 使用情况（过去 6 个月）及其相关性。检查的相关性包括过去 6 个月内的人口特征和艾滋病毒相关行为。使用对数二项式回归评估与近期 PrEP 使用的关联。 1776 名参与者中有 400 名 (22.5%) 报告了最近使用 PrEP 的情况。在调整后的模型中，近期 PrEP 使用与曼哈顿居住相关[调整后患病率 (aPR) 1.26； 95% 置信区间 (CI) (1.04, 1.53)]，收入较高 [aPR 1.29； 95% CI (1.03, 1.62)]，并且有保险 [aPR 1.89； 95% CI (1.33, 2.69)].除注射吸毒外，所有与 HIV 相关的行为均与 PrEP 的使用相关。需要更多的研究来更好地了解低收入和/或没有保险的患者使用 PrEP 的障碍，因为这可能有助于改善当前的公共卫生工作，以提高受影响人群中 PrEP 的采用率。
We examined recent pre-exposure prophylaxis (PrEP) use (past 6 months) and its correlates among a large sample of men who have sex with men and transgender and gender non-conforming persons participating in a home HIV self-testing program conducted by the New York City Health Department between 11/2016 and 1/2017. Correlates examined included demographic characteristics and HIV-related behaviors in the past 6 months. Associations with recent PrEP use were assessed using log-binomial regression. 400 (22.5%) of 1776 participants reported recent PrEP use. In adjusted models, recent PrEP use was associated with Manhattan residence [adjusted prevalence ratio (aPR) 1.26; 95% confidence interval (CI) (1.04, 1.53)], higher income [aPR 1.29; 95% CI (1.03, 1.62)], and having insurance [aPR 1.89; 95% CI (1.33, 2.69)]. All HIV-related behaviors, except for injection drug use, were individually associated with PrEP use. More research is needed to better understand barriers to PrEP use among patients who are low income and/or uninsured as this may help improve current public health efforts to increase PrEP uptake among disproportionately impacted populations.