Conversion of antibacterial activity of graphene-coated textiles through surface polarity
Conversion of antibacterial activity of graphene-coated textiles through surface polarity
复制标题
通过表面极性转化石墨烯涂层纺织品的抗菌活性
DOI：
10.1002/nano.202100226
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Rodrigues D
中科院分区：
文献类型：
--
作者：
Rodrigues D
石墨烯在许多可穿戴和生物医学应用中出现。了解石墨烯基纳米复合材料对细菌活性的影响对于设计适当的技术解决方案至关重要。在这项工作中，测试了单层和少层石墨烯对革兰氏阴性和革兰氏阳性模型细菌的抗菌活性。这种石墨烯基纳米材料对细菌活力有不同的影响，取决于浓度和形状。掺杂剂的存在可以增加或逆转石墨烯抗菌效果。在其他杀菌机制中，我们还证明了石墨烯表面极性与抗菌性能有关，并且可以通过表面电荷转移掺杂轻松进行改性。这种亲电性调节为石墨烯抗菌活性的分子基础提供了一种新的机制。
Graphene is emerging in numerous wearable and biomedical applications. Understanding the impact of graphene‐based nanocomposites over bacterial activity is critical for design appropriate technical solutions. In this work, antibacterial activity of monolayer and few‐layer graphene is tested against Gram‐negative and Gram‐positive model bacteria. Such graphene‐based nanomaterials present different effects on bacteria viability, depending on concentration and shape. The presence of dopant agents can either increase or revert graphene antibacterial effect. Among other bactericidal mechanisms, we also demonstrate that graphene surface polarity is connected to antibacterial properties and can be easily modified by surface charge transfer doping. This electrophilicity tuning offers a novel mechanism for the molecular basis of graphene's antibacterial activity.