MATURATION OF CORTICOSPINAL TRACTS ASSESSED BY ELECTROMAGNETIC STIMULATION OF THE MOTOR CORTEX
MATURATION OF CORTICOSPINAL TRACTS ASSESSED BY ELECTROMAGNETIC STIMULATION OF THE MOTOR CORTEX
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DOI：
10.1136/adc.63.11.1347
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发表时间：
1988-11-01
影响因子：
5.2
通讯作者：
EYRE, JA
中科院分区：
文献类型：
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作者：
KOH, THHG;EYRE, JA
使用电磁刺激可以激发成人的运动皮层，并且诱发肌肉动作电位的潜伏期可以评估皮质脊髓束的完整性。我们将这种技术应用于儿童来描述皮质脊髓束的成熟。记录从皮质刺激到诱发肌肉动作电位出现的潜伏期以及受试者的身高。将受试者的身高除以诱发肌肉动作电位开始的潜伏期，以提供下行运动通路 (VI) 内的传导速度指数。对包括早产儿在内的儿童的运动皮层进行电磁刺激后，有可能唤起肌肉动作电位，并且在8至11岁之间对刺激的敏感性逐步增加。此外，VI随着年龄的增长而逐渐增加；成人值在大约 11 岁时达到。这项技术在儿童中的成功应用表明，运动皮层的电磁刺激有可能检测新生儿和幼儿运动通路的异常情况。
The motor cortex can be excited in adults using electromagnetic stimulation, and the latency to the evoked muscle action potential allows an assessment of the integrity of corticospinal tracts. We applied this technique in children to describe the maturation of corticospinal tracts. The latency from cortical stimulation to the onset of the evoked muscle action potentials and the subject''s height were recorded. The subject''s height was divided by the latency to the onset of the evoked muscle action potential to provide an index of the conduction velocity within descending motor pathways (VI). It is possible to evoke muscle action potentials after electromagnetic stimulation of the motor cortex in children including preterm babies and there is a stepwise increase in the sensitivity to stimulation between 8 and 11 years of age. In addition there is a progressive increase in VI with age; adult values are attained at about 11 years The successful application of this technique in children suggests that electromagnetic stimulation of the motor cortex has the potential to allow detection of abnormality in motor pathways in newborn babies and young children.