Cooperation and conflict in the social amoeba Dictyostelium discoideum.
Cooperation and conflict in the social amoeba Dictyostelium discoideum.
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社会阿米巴盘基网柄菌中的合作与冲突。
DOI：
10.1387/ijdb.190158jm
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
J. Strassmann
中科院分区：
文献类型：
--
作者：
J. Medina;P. Shreenidhi;T. Larsen;D. Queller;J. Strassmann
群居变形虫盘齿骨虫对合作与冲突的进化提供了相当深刻的见解。在饥饿的情况下，盘状阿米巴变形虫在茎上合作形成一个由耐寒孢子组成的子实体。茎的发育是利他的，因为茎细胞的死亡有助于孢子的扩散。自然界子实体中细胞的高度亲缘关系意味着这种利他主义往往有利于亲属。然而，由于子实体是通过聚集体形成的，因此非亲缘体有可能加入聚集体，并在孢子和茎的命运上产生冲突。欺骗在群居变形虫的嵌合体中很常见，其中一种基因型经常利用另一种基因型产生更多的孢子。这种社会冲突在自然界中是一种重要的力量，与欺骗及其抵抗有关的基因的快速适应性进化表明了这一点。然而，欺骗可以通过高亲缘关系、通过tgr基因的异体识别、多效性和进化抗性来防止。未来的研究途径合作和冲突d discoideum包括性周期以及d discoideum及其细菌共生体之间的关系。disideum在实验室中的可驯服性以及其不寻常的聚集多细胞模式使其成为未来研究合作与冲突的有希望的模型。
The social amoeba Dictyostelium discoideum has provided considerable insight into the evolution of cooperation and conflict. Under starvation, D. discoideum amoebas cooperate to form a fruiting body comprised of hardy spores atop a stalk. The stalk development is altruistic because stalk cells die to aid spore dispersal. The high relatedness of cells in fruiting bodies in nature implies that this altruism often benefits relatives. However, since the fruiting body forms through aggregation there is potential for non-relatives to join the aggregate and create conflict over spore and stalk fates. Cheating is common in chimeras of social amoebas, where one genotype often takes advantage of the other and makes more spores. This social conflict is a significant force in nature as indicated by rapid rates of adaptive evolution in genes involved in cheating and its resistance. However, cheating can be prevented by high relatedness, allorecognition via tgr genes, pleiotropy and evolved resistance. Future avenues for the study of cooperation and conflict in D. discoideum include the sexual cycle as well as the relationship between D. discoideum and its bacterial symbionts. D. discoideum's tractability in the laboratory as well as its uncommon mode of aggregative multicellularity have established it as a promising model for future studies of cooperation and conflict.
野生社会阿米巴原虫微生物利他主义和作弊的遗传特征
DOI：
10.1073/pnas.1720324115
发表时间：
2018
期刊：
Proceedings of the National Academy of Sciences
影响因子：
--
作者：
Noh, Suegene;Geist, Katherine S.;Tian, Xiangjun;Strassmann, Joan E.;Queller, David C.
通讯作者：
Queller, David C.
DOI：
10.1073/pnas.1716087115
发表时间：
2018-05-22
影响因子：
11.1
作者：
Madgwick, Philip G.;Stewart, Balint;Wolf, Jason B.
通讯作者：
Wolf, Jason B.
缺乏F-box蛋白的盘基网柄菌阿米巴形成孢子，而不是野生型嵌合体中的茎。
DOI：
10.1073/pnas.97.7.3292
发表时间：
2000
影响因子：
11.1
作者：
Ennis,HL;Dao,DN;Pukatzki,SU;Kessin,RH
通讯作者：
Kessin,RH