MEDIAL SEPTAL-LESIONS RETARD CLASSICAL-CONDITIONING OF THE NICTITATING-MEMBRANE RESPONSE IN RABBITS

MEDIAL SEPTAL-LESIONS RETARD CLASSICAL-CONDITIONING OF THE NICTITATING-MEMBRANE RESPONSE IN RABBITS
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DOI:
10.1126/science.451592
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发表时间:
1979-01-01
期刊:
影响因子:
56.9
通讯作者:
THOMPSON, RF
THOMPSON, RF
中科院分区:
综合性期刊1区
文献类型:
--
作者:
BERRY, SD;THOMPSON, RF

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在瞬膜反应的经典条件反射之前,在14只家兔中的7只中产生了内侧隔病变。病变显著改变海马EEG,衰减条件海马单位反应,并减慢行为的收购率。行为结果与大量隔或海马消融的研究结果的对比表明隔-海马系统在学习中的功能细分。
Lesions of the medial septum were produced in 7 of 14 rabbits prior to classical conditioning of the nictitating membrane response. Lesions significantly altered the hippocampal EEG, attenuated conditioned hippocampal unit responses, and slowed the behavioral rate of acquisition. The contrast of the behavioral results with those of studies of massive septal or hippocampal ablation suggests a functional subdivision of the septo-hippocampal system in learning.