Obstetric, somatic, and demographic risk factors for postpartum depressive symptoms
Obstetric, somatic, and demographic risk factors for postpartum depressive symptoms
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DOI：
10.1016/s0029-7844(01)01722-7
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发表时间：
2002-02-01
影响因子：
7.2
通讯作者：
Sydsjö, G
中科院分区：
文献类型：
--
作者：
Josefsson, A;Angelsiöö, L;Sydsjö, G
目的：确定并检验妊娠期产后抑郁症状及围产儿死亡的潜在独立危险因素的预测能力。方法：采用病例对照研究，选取有产后抑郁症状的产妇132例作为指标组，无抑郁症状的产妇264例作为对照组。从标准化医疗记录中收集与社会人口状况、医疗、妇科和产科史、妊娠和围产期事件相关的数据。结果：产后抑郁症状的最强危险因素是孕期请病假和频繁去产前保健诊所。怀孕期间的并发症，如呕吐、早宫和精神障碍在产后抑郁症组中更为常见。未发现胎次、社会人口统计数据或分娩方式与产后抑郁症状之间存在关联。结论：产后抑郁症的高危妇女可以在怀孕期间被识别出来。最强的危险因素，怀孕期间的病假和多次去产前保健诊所，不是病因，可能是行为或生物起源。遗传易感性和激素变化的可能性值得进一步调查，以达到更彻底的了解。(C) 2002年由美国妇产科医师学会发布。
OBJECTIVE: To identify and test the predictive power of potential independent risk factors of postpartum depressive symptoms during pregnancy and die perinatal period.METHODS: We conducted a case-control study where 132 women with postpartum depressive symptoms were selected as an index group and 264 women without depressive symptoms as a control group. Data related to sociodemographic status, medical, gynecologic, and obstetric history, pregnancy, and perinatal events were collected from standardized medical records.RESULTS: The strongest risk factors for postpartum depressive symptoms were sick leave during pregnancy and a high number of visits to the antenatal care clinic. Complications during pregnancy, such as hyperemesis, premature contractions, and psychiatric disorder were more common in the postpartum depressed group of women. No association was found between parity, sociodemographic data, or mode of delivery and postpartum depressive symptoms.CONCLUSION: Women at risk for postpartum depression can be identified during pregnancy. The strongest risk factors, sick leave during pregnancy and many visits to the antenatal care clinic, are not etiologic and might be of either behavioral or biologic origin. The possibilities of genetic vulnerability and hormonal changes warrant further investigation to reach a more thorough understanding. (C) 2002 by the American College of Obstetricians and Gynecologists.