The effect of short-term air pollutants exposure on outpatient admission for blepharitis in Shanghai, China: a hospital-based study
The effect of short-term air pollutants exposure on outpatient admission for blepharitis in Shanghai, China: a hospital-based study
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DOI：
10.1007/s11356-023-25605-5
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发表时间：
2023-02
影响因子：
5.8
通讯作者：
Han Zhao;Tong Lin;Yun Yang;Changming Feng;Wushuang Wang;Lan Gong
中科院分区：
文献类型：
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作者：
Han Zhao;Tong Lin;Yun Yang;Changming Feng;Wushuang Wang;Lan Gong
睑缘炎是一种非常常见的眼科疾病，很少有研究检查空气污染物是否会导致睑缘炎的风险。我们调查了中国上海市暴露于空气污染和因睑缘炎而门诊就诊之间是否存在任何潜在的相关性。收集了2017年1月至2022年7月期间因睑缘炎每日门诊入院的数据。空气污染和气象数据来自上海市环境保护局。利用分布滞后非线性模型（DLNM）研究了大气污染物与睑缘炎的关系。进行季节分层分析。总共招募了10，681名睑缘炎患者。在单一污染物模型中，< 2.5 μm PM2.5和10 μm PM10的颗粒物增加10 μg/m3以及二氧化硫（SO2）和一氧化碳（CO）增加100 μg/m3与眼睑炎的门诊就诊显著相关。在多污染物模型中，臭氧（O3）和二氧化氮（NO2）增加10 μg/m3以及一氧化碳（CO）增加100 μg/m3与眼睑炎门诊就诊显著相关。此外，夏季睑缘炎与PM2.5和O3之间存在明显关系，冬季睑缘炎与PM10、NO2和SO2之间存在明显关系。暴露于短期空气污染会增加中国上海睑缘炎门诊就诊的风险。
Blepharitis is a very common ophthalmologic disease, and few studies have examined if air pollutants contribute to the risk of blepharitis. We investigated the presence of any potential correlation between exposure to air pollution and outpatient admission for blepharitis in Shanghai, China. Data on daily outpatient admission for blepharitis were collected from January 2017 to July 2022. Air pollution and meteorological data were acquired from the Shanghai Environmental Protection Agency. Using the distributed lag non-linear model (DLNM) we investigated the relationship between air pollutants and blepharitis. Seasonal stratified analysis was carried out. In total, 10,681 blepharitis patients were recruited. In the single-pollutant model, a 10 μg/m3increase in particulate matter with < 2.5 μm PM2.5and 10 μm PM10along with sulfur dioxide (SO2) and 100 μg/m3increase in carbon monoxide (CO) was significantly associated with outpatient visits for blepharitis. In the multi-pollutant model, a 10 μg/m3increase in ozone (O3) and nitrogen dioxide (NO2) and a 100 μg/m3increase in carbon monoxide (CO) was significantly associated with outpatient visits for blepharitis. Moreover, there was an obvious relationship between blepharitis and PM2.5and O3in the summers and blepharitis and PM10, NO2, and SO2during the winters. Exposure to short-term air pollution increases the risk of blepharitis outpatient visits in Shanghai, China.