An efficient one-pot asymmetric synthesis of biaryl compounds via Diels-Alder/retro-Diels-Alder cascade reactions.
An efficient one-pot asymmetric synthesis of biaryl compounds via Diels-Alder/retro-Diels-Alder cascade reactions.
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DOI：
10.1021/ol063013b
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发表时间：
2007-02
期刊：
影响因子：
5.2
通讯作者：
Yongxian Liu;K. Lu;M. Dai;Kai Wang;Wanqing Wu;Jia-Hua Chen;J. Quan;Zhen Yang
中科院分区：
文献类型：
--
作者：
Yongxian Liu;K. Lu;M. Dai;Kai Wang;Wanqing Wu;Jia-Hua Chen;J. Quan;Zhen Yang
[反应：报道了一种通过Diels-桤木/retro-Diels-桤木级联反应构建第二个芳环来合成轴向手性联芳基化合物的一步手性转移方法。该方法在天然产物和不对称催化剂的合成中具有广泛的应用前景。
[reaction: see text] A single-step chirality transfer method for the synthesis of axially chiral biaryl compounds by construction of the second aromatic ring via a Diels-Alder/retro-Diels-Alder cascade reaction is reported. This methodology should find broad application in the synthesis of natural products and asymmetric catalysts.