Boronic Acid-Functionalized Particles with Flexible Three-Dimensional Polymer Branch for Highly Specific Recognition of Glycoproteins
Boronic Acid-Functionalized Particles with Flexible Three-Dimensional Polymer Branch for Highly Specific Recognition of Glycoproteins
复制标题
具有柔性三维聚合物支链的硼酸功能化颗粒可用于糖蛋白的高度特异性识别
DOI：
10.1021/acsami.6b01829
复制
发表时间：
2016-04-20
影响因子：
9.5
通讯作者：
Zhang, Yukui
中科院分区：
文献类型：
--
作者：
Liu, Jianxi;Yang, Kaiguang;Zhang, Yukui
A novel organic inorganic hybrid particle with high hydrophilicity three-dimensional boronic acid functional polymer branches was facilely synthesized through thiol-ene surface-initiated click reaction, by which the target glycoprotein could be captured selectively in the 5000-fold disrupting protein. This highest selectivity ever reported demonstrated that this boronic acid functionalized particle exhibited great potential in the recognition of cis-diol-containing biomolecules, including the glycoproteins.
