Association of Long-term Exposure to Community Noise and Traffic-related Air Pollution With Coronary Heart Disease Mortality
Association of Long-term Exposure to Community Noise and Traffic-related Air Pollution With Coronary Heart Disease Mortality
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DOI：
10.1093/aje/kwr424
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发表时间：
2012-05-01
影响因子：
5
通讯作者：
Brauer, Michael
中科院分区：
文献类型：
--
作者：
Gan, Wen Qi;Davies, Hugh W.;Brauer, Michael
在大都市地区，道路交通是造成环境空气污染的主要因素，也是社区噪音的主要来源。作者在一项以人群为基础的队列研究中调查了社区噪声和交通相关空气污染对冠心病（CHD）死亡风险的独立和联合影响，暴露期为5年（1994年1月至1998年12月），随访期为4年（1999年1月至2002年12月）。纳入了暴露期间居住在加拿大大都市温哥华、年龄在45-85岁之间且基线时未患已知CHD的个体（n = 445，868）。个人暴露于社区噪声和交通相关的空气污染物，包括黑碳，颗粒物小于或等于2.5 μ m的空气动力学直径，二氧化氮和一氧化氮，估计在每个人的住所，分别使用噪声预测模型和土地利用回归模型。CHD死亡从省级死亡登记数据库中确定。在校正了包括交通相关空气污染物或噪音在内的潜在混杂因素后，噪音和黑碳水平升高至四分位距分别与CHD死亡率增加6%（95%置信区间：1，11）和4%（95%置信区间：1，8）相关。与最低十分位的人相比，最高十分位的受试者CHD死亡率增加22%（95%置信区间：4，43）。这些结果表明，交通相关的噪音和空气污染对冠心病死亡率有独立的影响。
In metropolitan areas, road traffic is a major contributor to ambient air pollution and the dominant source of community noise. The authors investigated the independent and joint influences of community noise and traffic-related air pollution on risk of coronary heart disease (CHD) mortality in a population-based cohort study with a 5-year exposure period (January 1994-December 1998) and a 4-year follow-up period (January 1999-December 2002). Individuals who were 45-85 years of age and resided in metropolitan Vancouver, Canada, during the exposure period and did not have known CHD at baseline were included (n = 445,868). Individual exposures to community noise and traffic-related air pollutants, including black carbon, particulate matter less than or equal to 2.5 mu m in aerodynamic diameter, nitrogen dioxide, and nitric oxide, were estimated at each person's residence using a noise prediction model and land-use regression models, respectively. CHD deaths were identified from the provincial death registration database. After adjustment for potential confounders, including traffic-related air pollutants or noise, elevations in noise and black carbon equal to the interquartile ranges were associated with 6% (95% confidence interval: 1, 11) and 4% (95% confidence interval: 1, 8) increases, respectively, in CHD mortality. Subjects in the highest noise decile had a 22% (95% confidence interval: 4, 43) increase in CHD mortality compared with persons in the lowest decile. These findings suggest that there are independent effects of traffic-related noise and air pollution on CHD mortality.