Intravascular MR imaging-guided balloon angioplasty with an MR imaging guide wire: Feasibility study in rabbits
Intravascular MR imaging-guided balloon angioplasty with an MR imaging guide wire: Feasibility study in rabbits
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DOI：
10.1148/radiology.217.2.r00oc17501
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发表时间：
2000-11-01
期刊：
影响因子：
19.7
通讯作者：
Atalar, E
中科院分区：
文献类型：
--
作者：
Yang, XM;Atalar, E
目得：为了开发一种技术，血管内磁共振（MR）引导的球囊血管成形术与使用MR成像guidewire.Materials和方法：一个MR成像导丝（0.6毫米无环天线），可以放置在一个球囊导管制造。预期导丝可用作实时MR成像中的MR接收器探头或与介入器械一起使用的导丝。在8只家兔中进行剖腹术，并在上腹主动脉处形成可切除的狭窄。球囊血管成形术，在术前和术后MR主动脉造影中进行验证，并使用1.5 T MR装置进行肾脏对比度增强，该装置具有快速扰频梯度回波脉冲序列、短重复时间和回波时间以及每秒三帧的速率。结果：在MR跟踪期间，MR成像导丝的整个长度始终可见，为高信号强度带。在所有病例中，MR成像导丝均通过球囊扩张扩张的主动脉狭窄。在球囊血管成形术之前，狭窄远端的主动脉中的流量减少，这导致每个肾脏中的轻度对比增强。球囊血管成形术后，远端血流恢复，导致实质性的肾脏enhancement.CONCLUSION：磁共振成像导丝是一种潜在的工具，用于血管内介入磁共振成像。
PURPOSE: To develop a technique for intravascular magnetic resonance (MR)guided balloon angioplasty with use of an MR imaging guide wire.MATERIALS AND METHODS: An MR imaging guide wire (0.6-mm loopless antenna) that could be placed within a balloon catheter was manufactured. The guide wire was expected to function as either an MR receiver probe in real-time MR imaging or a guide wire for use with interventional devices. Laparotomy was performed in eight rabbits, and a dilatable stenosis was created at the upper abdominal aorta. Balloon angioplasty, Validated at pre- and postoperative MR aortography with renal contrast enhancement was performed by using a 1.5-T MR unit with a fast spoiled gradient-echo pulse sequence, short repetition and echo times, and a rate of three frames per second.RESULTS: During MR tracking, the entire length of the MR imaging guide wire was always visible as a band of high signal intensity. In all cases, the MR imaging guide wires were passed through the aortic stenoses dilated by means of balloon inflation. Before balloon angioplasty, flow in the aorta distal to the stenosis was decreased, which caused mild contrast enhancement in each kidney. After balloon angioplasty, distal flow was restored, resulting in substantial renal enhancement.CONCLUSION: The MR imaging guide wire is a potential tool for use in endovascular interventional MR imaging.