Surround inhibition in motor execution and motor imagery
Surround inhibition in motor execution and motor imagery
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DOI：
10.1016/j.neulet.2016.07.012
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发表时间：
2016-08-26
影响因子：
2.5
通讯作者：
Nagata, Hiroshi
中科院分区：
文献类型：
--
作者：
Aoyama, Toshiyuki;Kaneko, Fuminari;Nagata, Hiroshi
周围抑制（surround inhibition，SI）是一种集中神经元活动并促进选择性运动执行（selective motor execution，ME）的神经机制。本研究的目的是调查是否SI也产生在运动想象（MI）。此外，我们研究了MI期间SI的程度是否取决于ME期间SI的强度和/或MI的生动性。在示指屈曲的MI和ME过程中检查SI的范围。经颅磁刺激应用于休息，在启动的运动（相位阶段）和紧张性肌肉收缩的食指屈肌。运动诱发电位（MEP）记录从周围的肌肉，小指展肌（ADM）和协同肌肉，第一背侧骨间肌。ADM MEP的幅度在相位相期间降低，这表明SI发生在ME期间。在14例受试者中的7例中，在MI期间也观察到SI，尽管这种影响不显著。ME和MI期间SI的程度之间存在中度相关性。此外，在MI任务期间经历过生动MI的好成像者比差成像者表现出更强的SI。这些结果表明，共同的神经基板参与SI在ME期间至少部分在MI期间招募。在临床情况下，治疗性使用MI以产生生动的MI可能是发展SI强度的有效工具之一，有助于选择性执行所需的运动（C）2016 Elsevier爱尔兰Ltd.保留所有权利。
Surround inhibition (SI) is a neural mechanism to focus neuronal activity and facilitate selective motor execution (ME). The aim of the present study was to investigate whether SI is also generated during motor imagery (MI). Furthermore, we investigated whether the extent of SI during MI depends on the strength of SI during ME and/or vividness of MI. The extent of SI was examined during MI and ME of index finger flexion. Transcranial magnetic stimulation was applied at rest, during initiation of the movement (phasic phase) and during tonic muscle contraction of the index finger flexors. Motor evoked potentials (MEPs) were recorded from a surround muscle, abductor digiti minimi (ADM) and a synergistic muscle, the first dorsal interosseous muscle. The amplitude of ADM MEP was reduced during the phasic phase, which indicates that SI occurred during ME. In seven of 14 subjects, SI was also observed during MI, although this effect was not significant. There was a moderate correlation between the extent of SI during ME and MI. Furthermore, good imagers who experienced vivid MI during the MI task showed stronger SI than poor imagers. These results indicate that common neural substrates involved in SI during ME are at least in part recruited during MI. In clinical situations, the therapeutic use of MI to generate vivid MI may be one of effective tool to develop the strength of SI, which facilitate selective execution of desired movements (C) 2016 Elsevier Ireland Ltd. All rights reserved.