Channelrhodopsin engineering and exploration of new optogenetic tools

Channelrhodopsin engineering and exploration of new optogenetic tools
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DOI:
10.1038/nmeth.f.327
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发表时间:
2011-01-01
期刊:
影响因子:
48
通讯作者:
Moeglich, Andreas
Moeglich, Andreas
中科院分区:
生物学1区
文献类型:
--
作者:
Hegemann, Peter;Moeglich, Andreas

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来自微藻和真细菌的视紫红质是操纵神经元和其他细胞功能的强大工具,但这些工具仍然有局限性。我们讨论有助于推进光遗传学的工程方法。
Rhodopsins from microalgae and eubacteria are powerful tools for manipulating the function of neurons and other cells, but these tools still have limitations. We discuss engineering approaches that can help advance optogenetics.