p21-activated kinase signaling in breast cancer.
p21-activated kinase signaling in breast cancer.
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DOI:
10.1186/bcr961
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发表时间:
2005
期刊:
影响因子:
--
通讯作者:
Kumar R
中科院分区:
文献类型:
--
作者:
Gururaj AE;Rayala SK;Kumar R
The p21-activated kinases signal through a number of cellular pathways fundamental to growth, differentiation and apoptosis. A wealth of information has accumulated at an impressive pace in the recent past, both with regard to previously identified targets for p21-activated kinases that regulate the actin cytoskeleton and cellular stress pathways and with regard to newly identified targets and their role in cancer. Emerging data also provide new clues towards a previously unappreciated link between these various cellular processes. The present review attempts to provide a quick tutorial to the reader about the evolving significance of p21-activated kinases and small GTPases in breast cancer, using information from mouse models, tissue culture studies, and human materials.
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影响因子:
3.5
作者:
Balasenthil, S;Barnes, CJ;Kumar, R
通讯作者:
Kumar, R
影响因子:
4.8
作者:
Bayless, KJ;Davis, GE
通讯作者:
Davis, GE
影响因子:
4.8
作者:
Callow, MG;Clairvoyant, F;Smeal, T
通讯作者:
Smeal, T
影响因子:
4.8
作者:
Faure, S;Vigneron, S;Morin, N
通讯作者:
Morin, N
DOI:
10.1073/pnas.94.4.1092
发表时间:
1997-02-18
影响因子:
11.1
作者:
Brzeska, H;Knaus, UG;Korn, ED
通讯作者:
Korn, ED