OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Exercise 4: an international multicenter longitudinal study using the RA-MRI Score.
OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Exercise 4: an international multicenter longitudinal study using the RA-MRI Score.
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OMERACT 类风湿关节炎磁共振成像研究。
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
J. Edmonds
中科院分区：
文献类型：
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作者：
P. Conaghan;M. Lassere;M. Østergaard;C. Peterfy;F. McQueen;P. O'connor;P. Bird;B. Ejbjerg;M. Klarlund;R. Shnier;H. Genant;P. Emery;J. Edmonds
这项多读者、多中心研究的目的是评估读者间评分在疾病状态和进展评估中的可靠性。该练习涉及 10 组掌指（MCP，第 2 至第 5）关节和 10 组手腕磁共振图像，由来自 5 个国际中心的经验丰富的读者进行评分。使用全局评分（0-3）对每个部位的滑膜炎进行评分。根据骨量比例（0-10代表侵蚀和缺损，0-3代表水肿）评估8个MCP关节部位和15个腕部部位的骨异常。滑膜炎、糜烂和水肿的组内相关系数（ICC）和最小可检测差异是可以接受的，尽管状态评分比进展评分更好。 MCP 关节的一致性比手腕更好。某些结果的图像变化有限导致 ICC 较低。骨缺损的一致性最差，并且已从新的评分建议中删除。尽管培训有限，但多中心读者表现出了可接受的一致性水平。
The aim of this multireader, multicenter study was to assess the inter-reader reliability of the score in the assessment of disease status and progression. The exercise involved 10 sets of metacarpophalangeal (MCP, 2nd to 5th) joints and 10 sets of wrist magnetic resonance images that were scored by experienced readers from 5 international centers. Synovitis was scored for each site using a global score (0-3). Bone abnormalities were assessed at 8 MCP joint sites and 15 wrist sites according to proportion of bone volume (0-10 for erosions and defects and 0-3 for edema). Intraclass correlation coefficients (ICC) and smallest detectable differences for synovitis, erosions, and edema were acceptable, although better for status scores than progression scores. The agreement for MCP joints was better than wrists. Limited variation in the images for some findings resulted in low ICC. Bone defects had the poorest agreement and have been omitted from new scoring recommendations. Despite limited training, multicenter readers demonstrated acceptable levels of agreement.