Comparison of the Characteristics and Outcomes of COVID-19 Patients Treated by a Hospital-at-Home Service in Japan during the Alpha and Delta Waves.
Comparison of the Characteristics and Outcomes of COVID-19 Patients Treated by a Hospital-at-Home Service in Japan during the Alpha and Delta Waves.
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DOI：
10.3390/jcm11113185
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发表时间：
2022-06-02
影响因子：
3.9
通讯作者：
中科院分区：
文献类型：
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作者：
冠状病毒感染是由严重急性呼吸道综合征冠状病毒2（SARS-CoV-2）的不同变体引起的反复浪潮，每一波患者人数都在增加。在日本，当医院床位短缺时，私人下班后上门服务（AHHC）为需要氧气的病人提供在家住院（HaH）服务。这项回顾性研究旨在比较在SARS-CoV-2 α型（2021年3月至6月）和Delta型（2021年7月至12月）变异株引起的COVID-19浪潮期间接受AHHC服务治疗的COVID-19患者的特征。所有于2021年3月至12月期间接受AHHC服务治疗并等待住院的COVID-19患者均包括在内。数据收集自医疗记录和后续电话访谈。AHHC服务分别在Alpha和Delta波期间治疗了55名和273名COVID-19患者。在Delta波期间接受治疗的患者明显比在Alpha波期间接受治疗的患者年轻（中位数：分别为63岁和47岁; p < 0.001）。两种波之间的疾病严重程度无显著差异，但α波期间的粗病死率（10/55，18.2%）显著高于δ波期间（4/273，1.4%; p < 0.001）。患者特征和结局在α波和δ波之间存在差异。
Coronavirus infections occurred in repeated waves caused by different variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with the number of patients increasing during each wave. A private after-hours house-call (AHHC) service provides hospital-at-home (HaH) services to patients in Japan requiring oxygen when hospital beds are in short supply. This retrospective study aimed to compare the characteristics of COVID-19 patients treated by the AHHC service during the COVID-19 waves caused by the Alpha (March–June 2021) and Delta (July–December 2021) SARS-CoV-2 variants. All patients with COVID-19 treated by the AHHC service from March to December 2021 while awaiting hospitalization were included. The data were collected from medical records and follow-up telephone interviews. The AHHC service treated 55 and 273 COVID-19 patients during the Alpha and Delta waves, respectively. The patients treated during the Delta wave were significantly younger than those treated during the Alpha wave (median: 63 years and 47 years, respectively; p < 0.001). Disease severity did not differ significantly between the two waves, but the crude case-fatality rate was significantly higher during the Alpha wave (10/55, 18.2%) than during the Delta wave (4/273, 1.4%; p < 0.001). The patient characteristics and outcomes differed between the Alpha and Delta waves.
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DOI：
10.1016/s2468-2667(21)00055-4
发表时间：
2021-05
期刊：
The Lancet. Public health
影响因子：
--
作者：
Graham MS;Sudre CH;May A;Antonelli M;Murray B;Varsavsky T;Kläser K;Canas LS;Molteni E;Modat M;Drew DA;Nguyen LH;Polidori L;Selvachandran S;Hu C;Capdevila J;COVID-19 Genomics UK (COG-UK) Consortium;Hammers A;Chan AT;Wolf J;Spector TD;Steves CJ;Ourselin S
通讯作者：
Ourselin S
下班后家庭医疗服务在等待医院入院的Covid-19患者治疗中的作用：回顾性队列研究。
影响因子：
1.6
作者：
Inokuchi R;Jin X;Iwagami M;Ishikawa M;Tamiya N
通讯作者：
Tamiya N
影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
Cao, Bin
DOI：
10.1016/j.jamda.2021.01.077
发表时间：
2021-05
影响因子：
7.6
作者：
Nogués X;Sánchez-Martinez F;Castells X;Díez-Pérez A;Sabaté RA;Petit I;Brasé A;Horcajada JP;Güerri-Fernández R;Pascual J
通讯作者：
Pascual J
影响因子：
4.3
作者：
Cao, Zicheng;Qiu, Zekai;Du, Xiangjun
通讯作者：
Du, Xiangjun