EVALUATION OF HYPOCARBIA AND HYPERCARBIA DURING CAROTID ENDARTERECTOMY
EVALUATION OF HYPOCARBIA AND HYPERCARBIA DURING CAROTID ENDARTERECTOMY
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DOI：
10.1161/01.str.7.5.451
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发表时间：
1976-01-01
期刊：
影响因子：
8.3
通讯作者：
HOYT, JL
中科院分区：
文献类型：
--
作者：
BAKER, WH;RODMAN, JA;HOYT, JL
连续患者[36]在颈动脉内膜切除术期间随机接受低碳酸（PaCO2 [动脉二氧化碳分压] < 25托）或高碳酸（PaCO2 > 60托）全身麻醉，以测试两种方案对术后神经功能缺损发生率的影响。未使用留置分流器。 1 名患者死亡，2 名患者出现永久性神经功能缺损，2 名患者出现暂时性神经功能缺损。尽管低碳患者的神经并发症比高碳患者少，但差异无统计学意义（P < 0.13）。高碳酸血症显着增加术中心律失常的发生率。未发现术后脑卒中发生率与颈内动脉背压或颈动脉闭塞时间之间存在关系。
Consecutive patients [36] were randomly given hypocarbic (PaCO2 [arterial partial pressure of carbon dioxide] < 25 torr) or hypercarbic (PaCO2 > 60 torr) general anesthesia during carotid endarterectomy to test the effect of the 2 regimens upon the incidence of postoperative neurological deficit. An indwelling shunt was not used. One patient died, 2 have permanent neurological deficits and 2 have temporary neurological deficits. Although hypocarbic patients had fewer neurological complications than hypercarbic patients, the difference was not statistically significant (P < 0.13). Hypercarbia significantly increased the incidence of intraoperative arrhythmia. No relationship was found between the incidence of postoperative stroke and the internal carotid back pressure or the time of carotid occlusion.