Instrumentation of the ESRF medical imaging facility
Instrumentation of the ESRF medical imaging facility
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DOI：
10.1016/s0168-9002(99)00167-9
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发表时间：
1999-06-04
影响因子：
1.4
通讯作者：
Le Bas, JF
中科院分区：
文献类型：
--
作者：
Elleaume, H;Charvet, AM;Le Bas, JF
在欧洲同步加速器辐射设施（ESRF），一个光束口已被用于医学研究计划。已经建造了两个设施供替代运行。第一个致力于医学成像，重点是静脉内冠状动脉造影和计算机断层扫描（CT）。第二个设施专门用于临床前微束放射治疗（MRT）。本文介绍了成像设备的仪器。设计了两个单色器，它们都是基于劳厄几何中的弯曲硅晶体。一个多功能的扫描设备已经建成的预对准和扫描的病人通过X射线束在放射摄影或CT模式。本征锗检测器与大动态范围电子器件（16位）一起使用以获取数据。束线目前正处于调试阶段的最后阶段;静脉内冠状动脉造影术计划于1999年开始与病人和CT临床前计划正在进行中的小动物。在血管造影和CT模式下获得的第一批动物体内图像用于说明这些器械的性能。(C)1999 Elsevier Science B. V.保留所有权利。
At the European Synchrotron Radiation Facility (ESRF) a beamport has been instrumented for medical research programs. Two facilities have been constructed for alternative operation. The first one is devoted to medical imaging and is focused on intravenous coronary angiography and computed tomography (CT). The second facility is dedicated to pre-clinical microbeam radiotherapy (MRT). This paper describes the instrumentation for the imaging facility. Two monochromators have been designed, both are based on bent silicon crystals in the Laue geometry. A versatile scanning device has been built for pre-alignment and scanning of the patient through the X-ray beam in radiography or CT modes. An intrinsic germanium detector is used together with large dynamic range electronics (16 bits) to acquire the data. The beamline is now at the end of its commissioning phase; intravenous coronary angiography is intended to start in 1999 with patients and the CT pre-clinical program is underway on small animals. The first in vivo images obtained on animals in angiography and CT modes are presented to illustrate the performances of these devices. (C) 1999 Elsevier Science B.V. All rights reserved.