Evaluation of Azithromycin Resistance in Treponema pallidum Specimens From Madagascar
Evaluation of Azithromycin Resistance in Treponema pallidum Specimens From Madagascar
复制标题
DOI：
10.1097/olq.0b013e3181bd11dd
复制
发表时间：
2009-12-01
影响因子：
3.1
通讯作者：
Hook, Edward
中科院分区：
文献类型：
--
作者：
Van Damme, Kathleen;Behets, Frieda;Hook, Edward
美国、加拿大和爱尔兰已有梅毒螺旋体对阿奇霉素耐药的记录。我们在马达加斯加 141 名梅毒病变患者的标本中没有发现对阿奇霉素耐药的证据，表明耐药性在地理上是孤立的，并支持使用阿奇霉素作为马达加斯加早期梅毒的替代治疗。
Treponema pallidum resistance to azithromycin has been documented in the US, Canada, and Ireland. We found no evidence of resistance to azithromycin in specimens from 141 patients with syphilitic lesions in Madagascar suggesting resistance is geographically isolated and supporting use of azithromycin as alternative treatment for early syphilis in Madagascar.