A NMR analysis of boromycin sodium complex and sodium desvalinoboromycinate
A NMR analysis of boromycin sodium complex and sodium desvalinoboromycinate
复制标题
硼霉素钠复合物和去缬氨硼霉素钠的NMR分析
DOI：
10.1021/jo00354a010
复制
发表时间：
1986
影响因子：
3.6
通讯作者：
H. Floss
中科院分区：
文献类型：
--
作者：
T. Somers;James D White;Jung Joon Lee;P. Keller;Ching‐jer Chang;H. Floss
Detailed and 13C NMR assignments were made to the sodium complexof boromycin (7) by using two-dimensional chemical shift correlation, NOE difference spectroscopy, and long-range heteronuclear shift correlation (LR-HETCOR). The latter technique was shown to provide a valuable means for assigning 13C signals, including the three carbonyl groups of 7, by establishing connectivities across quaternary carbons. Similar protocols were used for assigning! H NMR signals to the sodium derivativeof desvalinoboromycin (8). The results of NOE experiments on 7 are consistent with a solution conformation that approximates the tertiary structure of 2, as revealed by an X-ray crystalstructure.
