AN OPEN TRIAL OF EMOTION REGULATION THERAPY FOR GENERALIZED ANXIETY DISORDER AND COOCCURRING DEPRESSION
AN OPEN TRIAL OF EMOTION REGULATION THERAPY FOR GENERALIZED ANXIETY DISORDER AND COOCCURRING DEPRESSION
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DOI：
10.1002/da.22377
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发表时间：
2015-08-01
影响因子：
7.4
通讯作者：
Heimberg, Richard G.
中科院分区：
文献类型：
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作者：
Mennin, Douglas S.;Fresco, David M.;Heimberg, Richard G.
背景虽然CBT对各种精神疾病都有效，但与接受CBT治疗其他疾病的患者相比，GAD患者实现高终末状态功能的相对较少。此外，使用无显著抑郁症患者样本的GAD试验倾向于报告抑郁结局的效应量很小或在随访期间减少到治疗前水平。情绪调节疗法（ERT）整合了传统和当代的认知行为治疗的原则，从影响科学的基本和翻译的研究结果，提供了一个蓝图，通过专注于动机，监管和上下文学习mechanism.MethodThe的目的，这项调查是提供初步支持的疗效ERT在一个开放试验的患者与广泛性焦虑症和并发抑郁症状。21名患者接受了每周一次的20次ERT治疗。在治疗前、治疗中、治疗后以及3个月和9个月的随访中，对标准化的临床医师评分和自我报告措施进行评估。意向治疗analysisused.ResultsGAD患者，共病抑郁症的一半，证明统计学和临床有意义的改善症状的严重程度，损害，生活质量，并在模型相关的结果，包括情绪/动机强度，注意出席/接受，偏心，和认知重新评价。患者在三个月和九个月的随访periods.ConclusionsThese研究结果，虽然是初步的，情绪失调的发病，维护，现在治疗的条件，如广泛性焦虑症和并发抑郁症状的作用提供了额外的证据。
BackgroundAlthough CBT is efficacious for a wide variety of psychiatric conditions, relatively fewer GAD patients achieve high endstate functioning as compared to patients receiving CBTs for other disorders. Moreover, GAD trials that utilized patient samples without prominent depression have tended to report that effect sizes for depressive outcomes were small or diminished to pretreatment levels in the follow-up period. Emotion regulation therapy (ERT) integrates principles from traditional and contemporary cognitive behavioral treatments with basic and translational findings from affect science to offer a blueprint for improving intervention by focusing on motivational, regulatory, and contextual learning mechanisms.MethodThe purpose of this investigation was to provide initial support for the efficacy of ERT in an open trial of patients with GAD and cooccurring depressive symptoms. Twenty-one patients received a 20-session version of ERT delivered in weekly individual sessions. Standardized clinician ratings and self-report measures were assessed at pre-, mid-, and posttreatment as well as at three- and nine-month follow-ups. Intent-to-treat analyzes were utilized.ResultsGAD patients, half with comorbid major depression, evidenced statistically, and clinically meaningful improvements in symptom severity, impairment, quality of life, and in model-related outcomes including emotional/motivational intensity, mindful attending/acceptance, decentering, and cognitive reappraisal. Patients maintained gains across the three and nine month follow-up periods.ConclusionsThese findings, although preliminary, provide additional evidence for the role of emotion dysregulation in the onset, maintenance, and now treatment of conditions such as GAD and cooccurring depressive symptoms.