Individualized prevention against hypertension based on Traditional Chinese Medicine Constitution Theory: A large community-based retrospective, STROBE-compliant study among Chinese population.
Individualized prevention against hypertension based on Traditional Chinese Medicine Constitution Theory: A large community-based retrospective, STROBE-compliant study among Chinese population.
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基于中医体质理论的高血压个体化预防：一项大型社区回顾性、符合STROBE标准的中国人群研究。
DOI：
10.1097/md.0000000000008513
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发表时间：
2017-11
期刊：
影响因子：
1.6
通讯作者：
Yuan H
中科院分区：
文献类型：
--
作者：
Li Y;Li XH;Huang X;Yin L;Guo CX;Liu C;He YM;Liu X;Yuan H
补充数字内容可在文本中传统中医体质（TCMC）理论指出，具有偏见的TCMC的个体更有可能患有特定疾病。然而，关于TCMC对高血压易感性的影响知之甚少。本研究的目的是探讨TCMC与高血压之间的可能关系。使用STROBE指南检查表进行回顾性评价和观察。2009年至2013年在中国长沙进行了一项大型社区横断面研究。TCMC使用包括68个项目的问卷进行评估。分析TCMC的分布及不同类型TCMC与高血压风险的关系。总共有144，439名受试者接受了TCMC和血压（BP）评价。各中药组间高血压患病率差异有显著性意义（P <0.01）。调整后的Logistic回归模型显示，痰湿、阴虚、血瘀、气虚者更易患高血压。中医药相关临床特征分析表明，不同的中医药对应不同的西医高血压病分型，如痰湿高血压与肥胖高血压相似。提示痰湿、阴虚、血瘀、气虚对高血压患病率有不同的影响。应重视与高血压易感性相关的中药成分，针对不同的中药成分制定相应的预防和治疗措施。
Supplemental Digital Content is available in the text Traditional Chinese Medicine Constitution (TCMC) theory states that individuals with a biased TCMC are more likely to suffer from specific diseases. However, little is known regarding the influence of TCMC on susceptibility to hypertension. The aim of this study is to examine the possible relationship between TCMC and hypertension. Retrospective evaluation and observation were performed using the STROBE guidelines checklist. A large community-based cross-sectional study was conducted between 2009 and 2013 in Changsha, China. TCMC was assessed using a questionnaire that included 68 items. TCMC distributions and the associations of different TCMCs with hypertension risk were analyzed. In total, 144,439 subjects underwent evaluations of TCMC and blood pressure (BP). There were significant differences in the hypertension prevalence among the various TCMC groups (P < .01). An adjusted logistic regression model indicated that those with phlegm wetness, yin deficiency, blood stasis, or qi deficiency were more likely to have hypertension. Analysis of the clinical characteristics related to TCMC indicated that different TCMCs corresponded to different hypertension classifications using Western medicine criteria; for example, phlegm wetness with hypertension was similar to obesity-related hypertension. Our results suggest that phlegm wetness, yin deficiency, blood stasis, and qi deficiency have different effects on the prevalence of hypertension. More attention should be paid to TCMCs associated with susceptibility to hypertension, and corresponding preventive and therapeutic treatments should be developed according to different TCMCs.