Global burden of disease in young people aged 10-24 years: a systematic analysis
Global burden of disease in young people aged 10-24 years: a systematic analysis
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DOI：
10.1016/s0140-6736(11)60512-6
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发表时间：
2011-06-18
期刊：
影响因子：
168.9
通讯作者：
Mathers, Colin D.
中科院分区：
文献类型：
--
作者：
Gore, Fiona M.;Bloem, Paul J. N.;Mathers, Colin D.
10-24岁的年轻人占世界人口的27%。虽然这些年来出现了重要的健康问题和晚年疾病的风险因素，但对全球疾病负担的贡献尚不清楚。我们描述了全球的疾病负担，在年轻人和危险因素的贡献，burner.Methods，我们使用的数据来自世界卫生组织的2004年全球疾病负担的研究。世卫组织区域根据发病率、流行率、严重程度和死亡率的现有数据，估计了10-24岁青年人的特定原因残疾调整生命年。世卫组织成员国分为低收入、中等收入和高收入国家，并分为世卫组织区域。我们使用比较风险评估方法估计了可归因于特定全球健康风险因素的死亡率。DALYS被分为几年的寿命损失，因为过早死亡（YLLs）和年损失，因为残疾（YLDs），并按性别和5岁年龄组的地区。结果-事件DALYS在那些年龄在10-24岁的总人数约为2.36亿，占15.5%的DALYS为所有年龄组。非洲这一年龄组的残疾人比例最高，是高收入国家的2.5倍（每1000人中有208人对82人）。在各地区，15至19岁之间的女孩DALY率比男孩高12%（137比153）。在世界范围内，10-24岁青年人YLD的三个主要原因是神经精神疾病（45%），意外伤害（12%）和传染病和寄生虫病（10%）。在10-24岁的人群中，发生糖尿病的主要危险因素是酒精（7%）、不安全的性行为（4%）、缺铁（3%）、缺乏避孕措施（2%）和非法药物使用（2%）。然而，这一年龄组预防疾病和伤害的机会没有得到充分利用。这项研究的结果表明，青少年健康将受益于公众健康关注的增加。
Background Young people aged 10-24 years represent 27% of the world's population. Although important health problems and risk factors for disease in later life emerge in these years, the contribution to the global burden of disease is unknown. We describe the global burden of disease arising in young people and the contribution of risk factors to that burden.Methods We used data from WHO's 2004 Global Burden of Disease study. Cause-specific disability-adjusted life-years (DALYs) for young people aged 10-24 years were estimated by WHO region on the basis of available data for incidence, prevalence, severity, and mortality. WHO member states were classified into low-income, middle-income, and high-income countries, and into WHO regions. We estimated DALYs attributable to specific global health risk factors using the comparative risk assessment method. DALYs were divided into years of life lost because of premature mortality (YLLs) and years lost because of disability (YLDs), and are presented for regions by sex and by 5-year age groups.Findings The total number of incident DALYs in those aged 10-24 years was about 236 million, representing 15.5% of total DALYs for all age groups. Africa had the highest rate of DALYs for this age group, which was 2.5 times greater than in high-income countries (208 vs 82 DALYs per 1000 population). Across regions, DALY rates were 12% higher in girls than in boys between 15 and 19 years (137 vs 153). Worldwide, the three main causes of YLDs for 10-24-year-olds were neuropsychiatric disorders (45%), unintentional injuries (12%), and infectious and parasitic diseases (10%). The main risk factors for incident DALYs in 10-24-year-olds were alcohol (7% of DALYs), unsafe sex (4%), iron deficiency (3%), lack of contraception (2%), and illicit drug use (2%).Interpretation The health of young people has been largely neglected in global public health because this age group is perceived as healthy. However, opportunities for prevention of disease and injury in this age group are not fully exploited. The findings from this study suggest that adolescent health would benefit from increased public health attention.