Orthograde and retrograde axonal transport of dopamine-beta-hydroxylase in ileal mesenteric nerves of rats with chronic streptozotocin diabetes.
Orthograde and retrograde axonal transport of dopamine-beta-hydroxylase in ileal mesenteric nerves of rats with chronic streptozotocin diabetes.
复制标题
慢性链脲佐菌素糖尿病大鼠回肠肠系膜神经中多巴胺-β-羟化酶的顺行和逆行轴突转运。
DOI：
10.1016/0006-8993(87)91173-5
复制
发表时间：
1987
期刊：
影响因子：
2.9
通讯作者：
Grabau,GG
中科院分区：
文献类型：
--
作者：
Schmidt,RE;Modert,CW;Grabau,GG
Rats with chronic streptozotocin-induced diabetes develop a neuropathy involving the ileal mesenteric nerves. Distal portions of these postganglionic sympathetic axons develop markedly dilated, dopamine-β-hydroxylase (DBH)-containing dystrophic swellings. These findings led us to develop a quantitative method to examine orthograde and retrograde axonal transport of DBH in ileal mesenteric nerves. Surprisingly, no significant alteration in orthograde or retrograde axonal transport of DBH was identified.
