Qualitative evaluation of titanium implant integration into bone by diffraction enhanced imaging.
Qualitative evaluation of titanium implant integration into bone by diffraction enhanced imaging.
复制标题
通过衍射增强成像对钛植入物与骨的整合进行定性评估。
DOI：
10.1088/0031-9155/51/5/019
复制
发表时间：
2006
影响因子：
3.5
通讯作者：
Mollenhauer,J
中科院分区：
文献类型：
--
作者：
Wagner,A;Sachse,A;Keller,M;Aurich,M;Wetzel,W-D;Hortschansky,P;Schmuck,K;Lohmann,M;Reime,B;Metge,J;Arfelli,F;Menk,R;Rigon,L;Muehleman,C;Bravin,A;Coan,P;Mollenhauer,J
衍射增强成像(DEI)利用X射线在边缘处的折射，实现了材料边界的明显可视化，并排除了经常模糊边缘和模糊图像的散射。在这里，第一个证据是，使用DEI，对金属植入物与骨整合的质量进行无损评估是可能的。在兔子和绵羊身上进行了实验，研究了DEI作为植入物研究工具的选择。将从DEI获得的结果与从标本中获得的传统组织学进行比较。DE图像可以识别植入物的羟基磷灰石层中骨生长的质量。剩余间隙小于0.3 mm的种植体不完全整合导致种植体/骨交界处出现高屈光边缘。相比之下，骨完全长到表面的植入物不会显示屈光信号。因此，屈光信号可用于诊断种植体愈合和/或松动。
Diffraction enhanced imaging (DEI) uses refraction of x-rays at edges, which allows pronounced visualization of material borders and rejects scattering which often obscures edges and blurs images. Here, the first evidence is presented that, using DEI, a destruction-free evaluation of the quality of integration of metal implants into bone is possible. Experiments were performed in rabbits and sheep with model implants to investigate the option for DEI as a tool in implant research. The results obtained from DEI were compared to conventional histology obtained from the specimens. DE images allow the identification of the quality of ingrowth of bone into the hydroxyapatite layer of the implant. Incomplete integration of the implant with a remaining gap of less than 0.3 mm caused the presence of a highly refractive edge at the implant/bone border. In contrast, implants with bone fully grown onto the surface did not display a refractive signal. Therefore, the refractive signal could be utilized to diagnose implant healing and/or loosening.