Comparison of the different classification criteria sets for primary Sjogren's syndrome

Comparison of the different classification criteria sets for primary Sjogren's syndrome
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DOI:
10.1080/03009740600759860
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发表时间:
2006-01-01
影响因子:
2.1
通讯作者:
Tomsic, M.
Tomsic, M.
中科院分区:
医学4区
文献类型:
--
作者:
Novljan, M. P.;Rozman, B.;Tomsic, M.

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目的:评估原发性干燥综合征(pSS)的不同分类标准集的可比性:在一项前瞻性研究中,我们检查了所有疑似pSS的患者谁被接纳到我们的风湿病科或提到我们的门诊2001年1月1日至2002年12月31日之间。哥本哈根,加利福尼亚州,1996年欧洲和美国-欧洲共识组(美国-欧盟)的标准集被用来评估每个patient.Results:90的222例(41%)被诊断为pSS满足至少一个分类标准集。符合欧洲标准集的pSS患者数量最多(36%),其次是哥本哈根(28%),美国-欧盟(26%)和加利福尼亚(9%)标准集。平均而言,符合加州标准的患者组比其他三组患者年龄大5.6岁(p < 0.05)。此外,诊断前的疾病持续时间比其他三组长2.6年。符合加州标准或美国-欧盟标准的患者组的白细胞减少症患病率更高(p < 0.05)。符合美国-欧盟标准的患者关节炎患病率也较高(p < 0.05)。其他临床和实验室参数的患病率没有显着差异studyed.Conclusions:不同的患者被诊断为pSS,如果使用不同的分类标准集。因此,基于不同诊断pSS分类标准集的研究不具有直接可比性。
Objective: To assess the comparability of different classification criteria sets for primary Sjogren's syndrome (pSS).Methods: In a prospective study we examined all patients with suspected pSS who were admitted to our Department of Rheumatology or referred to our outpatient clinic between 1 January 2001 and 31 December 2002. The Copenhagen, Californian, 1996 European, and American-European consensus group (US-EU) criteria sets were used to assess each patient.Results: Ninety out of 222 patients (41%) were diagnosed with pSS by fulfilling at least one classification criteria set. The highest number of patients who were diagnosed with pSS fulfilled the European criteria set (36%), followed by the Copenhagen (28%), the US-EU (26%), and the Californian (9%) criteria sets. On average, the group of patients fulfilling the Californian criteria set were 5.6 years older than the patients in the other three groups (p < 0.05). In addition, the disease duration before diagnosis was 2.6 years longer than in the other three groups. The groups of patients fulfilling either the Californian or the US-EU criteria sets had a higher prevalence of leucopaenia (p < 0.05). Those fulfilling the US-EU criteria set also had a higher prevalence of arthritis (p < 0.05). No significant differences were found in the prevalence of the other clinical and laboratory parameters studied.Conclusions: Different patients are diagnosed with pSS if different classification criteria sets are used. Therefore, studies based on different classification criteria sets for diagnosing pSS are not directly comparable.