Renin-Like Enzyme in the Adrenal Gland

Renin-Like Enzyme in the Adrenal Gland
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肾上腺中的肾素样酶

DOI:
10.1126/science.158.3808.1589
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发表时间:
1967
期刊:
影响因子:
56.9
通讯作者:
J. Ryan
J. Ryan
中科院分区:
综合性期刊1区
文献类型:
--
作者:
J. Ryan

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兔肾上腺含有一种酶,它与肾素底物反应形成血管加压多肽,可能是血管紧张素i。鉴于血管紧张素对醛固酮和儿茶酚胺分泌的强烈影响,这一发现表明可能存在肾上腺内控制肾上腺分泌的机制。
The rabbit adrenal gland contains an enzyme which reacts with renin substrate to form a vasopressor polypeptide, probably angiotensin I. In view of the strong effects of angiotensin on secretion of aldosterone and catecholamine, this finding suggests that there may be an intra-adrenal mechanism for the control of adrenal secretions.