REACTIONS OF NEURONS IN OR NEAR SUPRAOPTIC NUCLEI
REACTIONS OF NEURONS IN OR NEAR SUPRAOPTIC NUCLEI
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DOI：
10.1152/ajplegacy.1962.202.3.487
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发表时间：
1962-01-01
影响因子：
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通讯作者：
USHIYAMA, J
中科院分区：
文献类型：
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作者：
BROOKS, CM;LANGE, G;USHIYAMA, J
研究了下丘脑视上核内或视上核附近的神经元对各种“刺激”的反应。少数神经元被发现兴奋的肌肉传入刺激。刺激腓肠肌和胫骨肌神经纤维可抑制其他神经元。刺激迷走神经激活了一些神经元，抑制了一些，但在肌肉神经刺激的情况下，绝大多数神经元不受影响。刺激中脑和脑桥网状结构抑制一些神经元，激活其他神经元。颈动脉内注射等渗盐水对神经元放电没有影响，但低浓度的葡萄糖增强神经元放电，高渗氯化钠。蒸馏水减少神经元活动。肾上腺素、去甲肾上腺素和乙酰胆碱加速神经元放电;阿托品在所用浓度下无影响。对注射材料的反应比神经刺激的效果更慢，持续时间更长。一些神经元受到几种刺激的影响，但大多数神经元在记录期间没有反应，可以保持。
The reactions of neurons within or near the supraoptic nuclei of the hypothalamus to a variety of "stimuli" were studied. A few neurons were found to be excited by stimulation of muscle afferents. Other neurons were inhibited by stimulation of gastrocnemius and tibialis nerve fibers. Stimulation of the vagus nerve activated some neurons and inhibited a few but, as in the case of muscle nerve stimulation, the vast majority of neurons were unaffected. Stimulation of midbrain and pontine reticular formation inhibited some neurons and activated others. Intracarotid injections of isotonic saline had no effect on neuron discharge but low concentrations of glucose augmented neuron firing as did hypertonic NaCl. Distilled water reduced neuron activity. Epinephrine, norepinephrine, and acetylcholine accelerated neuron firing; atropine was without effect in concentrations employed. Responses to injected materials developed more slowly and lasted longer than did effects of nerve stimulations. Some neurons were affected by several of the stimuli employed but the majority of neurons were unresponsive during the periods of recording which could be maintained.