A compendium of covariances and correlation coefficients of coalescent tree properties.

A compendium of covariances and correlation coefficients of coalescent tree properties.
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DOI:
10.1016/j.tpb.2021.09.008
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发表时间:
2022-03
影响因子:
1.4
通讯作者:
Rosenberg, Noah A.
Rosenberg, Noah A.
中科院分区:
生物学4区
文献类型:
--
作者:
Alimpiev, Egor;Rosenberg, Noah A.

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基因谱系的研究通常通过测量其高度(H)、长度(L)、外部分支的总和(E)、内部分支的总和(I)、两个基部分支的平均值(B)以及对其他谱系特征有贡献的聚结时间(T)来进行。这些树的属性和它们之间的关系可以提供深入了解群体遗传过程对系谱和遗传序列的影响。在这里,在合并模型下,我们研究了家谱树的15对特征之间的相关性:Hn,Ln,En,In,Bn和Tk,样本大小为n,其中2 ≤ k ≤ n。我们报告高相关性之间的Hn,Ln,In和Bn,与所有成对的这些量的相关性具有大于或等于在极限值,其中是黎曼zeta函数。虽然En对所有n的期望值为2,Hn在极限内的期望值为2,但它们的极限相关性为0。研究结果有助于理解聚结树的形状特征。
Gene genealogies are frequently studied by measuring properties such as their height (H), length (L), sum of external branches (E), sum of internal branches (I), and mean of their two basal branches (B), and the coalescence times that contribute to the other genealogical features (T ). These tree properties and their relationships can provide insight into the effects of population-genetic processes on genealogies and genetic sequences. Here, under the coalescent model, we study the 15 correlations among pairs of features of genealogical trees: Hn, Ln, En, In, Bn, and Tk for a sample of size n, with 2 ≤ k ≤ n. We report high correlations among Hn, Ln, In, and Bn, with all pairwise correlations of these quantities having values greater than or equal to in the limit as , where is the Riemann zeta function. Although En has expectation 2 for all n and Hn has expectation 2 in the limit, their limiting correlation is 0. The results contribute toward understanding features of the shapes of coalescent trees.
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