ISOTHERMAL UNFOLDING OF GLOBULAR PROTEINS IN AQUEOUS UREA SOLUTIONS

ISOTHERMAL UNFOLDING OF GLOBULAR PROTEINS IN AQUEOUS UREA SOLUTIONS
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DOI:
10.1021/ja01064a028
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发表时间:
1964-01-01
影响因子:
15
通讯作者:
TANFORD, C
TANFORD, C
中科院分区:
化学1区
文献类型:
--
作者:
TANFORD, C

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测量球状蛋白质在尿素水溶液中的展开给出的结果与基于“全有或全无”反应的计算结果不相容。结果表明,中间体是必须存在的,虽然还不能确切地知道它们的存在,但已经研究了它们的一些性质。
Measurements of the unfolding of globular proteins in aqueous urea solutions gives results which are incompatible with calculations based on an "all or none" reaction. It is indicated that intermediates must occur and although they are not known yet with certainty, some of their properties have been studied.