More than (where the target) meets the eyes: disrupted visuomotor transformations in optic ataxia.

More than (where the target) meets the eyes: disrupted visuomotor transformations in optic ataxia.
复制标题

超过(目标)遇到眼睛的多数:视觉性共济失调中的视觉运动变换。

DOI:
10.1016/j.neuropsychologia.2008.07.023
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发表时间:
2009-01
期刊:
影响因子:
2.6
通讯作者:
Coslett HB
Coslett HB
中科院分区:
心理学3区
文献类型:
--
作者:
Jax SA;Buxbaum LJ;Lie E;Coslett HB

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视觉引导的到达需要在以视网膜为中心的目标位置和以身体为中心的肢体位置之间的多个坐标系变换。视性共济失调(OA)的到达错误可能是由这些转换的中断引起的。与这一提议一致,先前的研究报告称,OA中的到达错误主要取决于目标相对于患者凝视的位置,而不管其相对于头部或身体中线的位置。我们试图通过测试KE来复制这一发现,KE是一名患有OA的患者,双侧顶叶和左侧运动前区病变(以及显著的非特异性白色疾病),他在完成一项任务时改变了头部和躯干的方向,同时保持目标的凝视相对位置不变(始终是中央凹)。与以前的报道相比,我们观察到,旋转头部或身体远离中线导致到达准确性下降。进一步的分析表明,多个视觉转换步骤可能已经中断KE。这些结果表明,凝视相对目标位置不是所有OA患者达到错误的唯一决定因素。
Visually-guided reaching entails multiple coordinate frame transformations between retina-centered target location and body-centered limb location. Reaching errors in optic ataxia (OA) may be caused by disruptions to these transformations. Consistent with this proposal, previous studies report that reaching errors in OA depend primarily on the location of a target relative to the patient’s gaze regardless of its location relative to the head or body midline. We attempted to replicate this finding by testing KE, a patient with OA following bilateral parietal and left premotor lesions (as well as significant non-specific white matter disease) on a reaching task that varied the orientation of his head and torso while holding the gaze-relative position of the target constant (always foveated). In contrast to previous reports, we observed that rotating the head or body away from the midline led to decreased reaching accuracy. Further analyses showed that multiple visuomotor transformation steps may have been disrupted in KE. These results suggest that gaze-relative target position is not the sole determinant of reaching errors in all OA patients.
DOI: 10.1093/brain/116.2.383
发表时间: 1993-04-01
期刊: BRAIN
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发表时间: 1994-04-01
期刊: NEUROPSYCHOLOGIA
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