Islet transplantation improves vascular diabetic complications in patients with diabetes who underwent kidney transplantation: A comparison between kidney-pancreas and kidney-alone transplantation.
Islet transplantation improves vascular diabetic complications in patients with diabetes who underwent kidney transplantation: A comparison between kidney-pancreas and kidney-alone transplantation.
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DOI：
10.1097/01.tp.0000061788.32639.d9
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发表时间：
2003-04-27
期刊：
影响因子：
6.2
通讯作者：
Secchi, A
中科院分区：
文献类型：
--
作者：
Fiorina, P;Folli, F;Secchi, A
背景本研究的目的是评估胰岛移植对患者生存率和糖尿病血管并发症的影响。37例1型尿毒症糖尿病肾移植患者接受胰岛移植（KI组）。尿毒症1型糖尿病肾胰腺联合移植组（KP组，n=162）、单纯肾移植组（KD组，n=42）和尿毒症1型糖尿病血液透析组（HD+DM组，n=196）作为生存率和内皮形态学的对照组。KI组和KP组的患者生存率相似，但高于HD+DM组（P
Background. The aim of this study was to evaluate the effects of islet transplantation on patient survival and diabetic vascular complications.Methods. Thirty-seven type 1 uremic diabetic kidney transplant patients underwent islet transplantation (KI group). Uremic type 1 diabetic kidney-pancreas (KP group, n=162), kidney-alone (KD group, n=42) transplant patients, and uremic type 1 diabetic patients still on hemodialysis (HD+DM group, n=196) constituted the control groups for survival and endothelial morphology.Results. Patient survival was similar in the KI and KP groups and higher than in the HD+DM group (P