Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth.
Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth.
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DOI：
10.1161/circresaha.114.304632
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发表时间：
2014-09-26
影响因子：
20.1
通讯作者：
Kühn B
中科院分区：
文献类型：
--
作者：
Zhang CH;Kühn B
Naqvi等人最近在Cell杂志上发表的一项研究表明，在青春期前的小鼠中，心肌细胞经历了与甲状腺激素激增有关的增殖爆发。该研究挑战了传统的末梢分化时间模型，为进一步研究心肌细胞增殖和分化的机制提供了方向。
A recent study from Naqvi et al in Cell shows that in mice during preadolescence, cardiomyocytes undergo a burst of proliferation that is related to a thyroid hormone surge. This study challenges the conventional model of the timing of terminal differentiation and provides a direction for further mechanistic research on cardiomyocyte proliferation and differentiation.