Monte Carlo simulation for MLC-based intensity-modulated radiotherapy.
Monte Carlo simulation for MLC-based intensity-modulated radiotherapy.
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DOI：
10.1016/s0958-3947(01)00061-9
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发表时间：
2001-01-01
期刊：
影响因子：
--
通讯作者：
Ma, C M
中科院分区：
文献类型：
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作者：
Pawlicki, T;Ma, C M
本文描述了基于多叶准直器(MLC)的调强放射治疗(IMRT)的光子束蒙特卡罗模拟。我们介绍了非蒙特卡罗放射治疗蒙特卡罗方法的一般方面，重点介绍了患者特定的放射治疗应用。蒙特卡罗方法可用于常规适形放射治疗中的调强放射治疗剂量验证、反向计划和正向计划。由于很难测量接近患者的异质模体中调强放射治疗的剂量分布，因此可以使用蒙特卡罗方法来验证使用传统方法计算的调强放射治疗剂量分布。此外，使用蒙特卡罗作为逆向计划的剂量计算方法，可以得到更优化的治疗计划。我们描述了这两个方面，并提供了我们的最新结果来说明讨论。最后，我们提出了目前蒙特卡罗剂量计算在临床应用中存在的问题。蒙特卡洛法是目前最新、最准确的放射治疗剂量计算方法。它目前正在由各种治疗计划供应商实施，并将在不久的将来用于临床。
This article describes photon beam Monte Carlo simulation for multi leaf collimator (MLC)-based intensity-modulated radiotherapy (IMRT). We present the general aspects of the Monte Carlo method for the non-Monte Carloist with an emphasis given to patient-specific radiotherapy application. Patient-specific application of the Monte Carlo method can be used for IMRT dose verification, inverse planning, and forward planning in conventional conformal radiotherapy. Because it is difficult to measure IMRT dose distributions in heterogeneous phantoms that approximate a patient, Monte Carlo methods can be used to verify IMRT dose distributions that are calculated using conventional methods. Furthermore, using Monte Carlo as the dose calculation method for inverse planning results in better-optimized treatment plans. We describe both aspects and present our recent results to illustrate the discussion. Finally, we present current issues related to clinical implementation of Monte Carlo dose calculation. Monte Carlo is the most recent, and most accurate, method of radiotherapy dose calculation. It is currently in the process of being implemented by various treatment planning vendors and will be available for clinical use in the immediate future.