Repurposing of existing antibiotics for the treatment of diabetes mellitus.

Repurposing of existing antibiotics for the treatment of diabetes mellitus.
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重新利用现有抗生素来治疗糖尿病。

DOI:
10.1007/978-3-319-17713-7_4
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发表时间:
2022
期刊:
In silico pharmacology
影响因子:
--
通讯作者:
Alam MS
Alam MS
中科院分区:
--
文献类型:
--
作者:
Alam MS

文献摘要

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大学孵化器(UI)通常被认为是大学衍生产品(USO)成功商业化的重要因素,超过一半的英国大学已经建立了校园UI。在这一章中,我们考察了UI在衍生过程中的价值,重点是位于UI中的USO的结构网络,与没有访问UI的大学中的USO进行比较。因此,我们的主要研究问题是:可以访问校园内用户界面的USO的结构网络在多大程度上与没有USO的USO不同?因此,这项研究促使人们越来越多地批评统计研究所在将学术研究商业化方面的有效性,并认识到参与网络带来的积极的直接和间接外部性。通过对两所研究密集型大学的所有USO的网络地图,我们描述和分析了USO与东道国大学内部和外部的各种合作伙伴的正式和非正式网络联系。通过访谈,我们还考虑了这些网络如何增强USO的资源和能力。我们的发现突出了显著的差异,无论是与其他USO还是在所在大学内,USO位于UI中的非正式联系更多,但正式联系更少。相比之下,孵化器的位置不会影响与外部组织联系的程度和性质。这些差异的原因是通过与大学组织的访谈来审查的,并指出了各种因素,包括孵化器和大学工作人员的积极中介作用、大学官僚机构、跨大学组织的执行董事会成员的隐藏网络、大学股权投资政策和补充技术。
University incubators (UI) are generally believed to be important in the successful commercialisation of university spin-outs (USO) with over half of all UK Universities having established an on-campus UI. In this chapter we examine the value of UIs in the spin-out process, focusing on the structural networks of USOs located in a UI as compared to USOs in a University with no access to a UI. Our primary research question is therefore: to what extent does the structural network of USOs with access to an on-campus UI differ from USOs without? The research therefore contributes to a growing critique of the effectiveness of UIs in commercialising academic research and the recognition of positive direct and indirect externalities from participation in networks. Through network mapping of all USOs from two research intensive universities, we profile and analyse the formal and informal network ties of USOs to various partners internal and external to the host university. Through interviews we also consider how these networks enhance the resources and capabilities of USOs. Our findings highlight significant differences, with USOs located in a UI having more informal but fewer formal ties, both to other USOs as well as within the host University. In contrast, location in an incubator was not found to affect the extent and nature of ties with external organisations. Reasons for these differences are examined through interviews with the USOs and point to various factors including the proactive brokering role of incubator and university staff, university bureaucracy, the hidden networks of executive board members across USOs, university equity investment policy and complementary technologies.