The effect of doxapram on buprenorphine induced respiratory depression.
The effect of doxapram on buprenorphine induced respiratory depression.
复制标题
多沙普仑对丁丙诺啡引起的呼吸抑制的作用。
作者：
J. Orwin
多沙普仑单次注射或输注给药可令人满意地抵消丁丙诺啡在健康受试者镇痛后1小时给药时产生的呼吸抑制。呼吸刺激作用的持续时间相对较短，然而，通过研究二氧化碳反应曲线的位移发现了更长的作用。
Doxapram administered as a single injection or infusion satisfactorily counteracted the respiratory depression produced by buprenorphrine when administered one hour after the analgesic in healthy subjects. The respiratory stimulant effect was relatively short lived, however, a more prolonged effect was found by study of the displacement of the carbon dioxide response curve.