PINEAL-GLAND - BIOLOGICAL CLOCK INVITRO
PINEAL-GLAND - BIOLOGICAL CLOCK INVITRO
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DOI：
10.1126/science.214852
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发表时间：
1978-01-01
期刊：
影响因子：
56.9
通讯作者：
REILLY, KB
中科院分区：
文献类型：
--
作者：
BINKLEY, SA;RIEBMAN, JB;REILLY, KB
通过跟踪体外鸡松果体中 N-乙酰转移酶活性的过程来研究昼夜节律。结果表明，在持续黑暗的器官培养的第一天，每天的变化取决于鸡被宰杀的时间；器官培养 6-7 天期间恒定黑暗中每日变化的持续性模棱两可；光的效果；肾上腺素能药物和放线菌酮的抑制；以及二丁酰环 AMP 和相关化合物的刺激。
Circadian rhythmicity was studied by following the course of N-acetyltransferase activity in the pineal glands of chickens in vitro. The results indicate a daily change during day 1 of organ culture in constant dark that was dependent on the time the chickens were killed; equivocal persistence of the daily change in constant dark during 6-7 days of organ culture; an effect of light; inhibition by adrenergic agents and cycloheximide; and stimulation by dibutyryl cyclic AMP and related compounds.