Compensation of motion artifacts in intracoronary optical frequency domain imaging and optical coherence tomography

Compensation of motion artifacts in intracoronary optical frequency domain imaging and optical coherence tomography
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DOI:
10.1007/s10554-011-9953-8
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发表时间:
2012-08-01
影响因子:
2.1
通讯作者:
Bouma, Brett E.
Bouma, Brett E.
中科院分区:
医学4区
文献类型:
--
作者:
Ha, Jinyong;Yoo, Hongki;Bouma, Brett E.

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冠状动脉内光学相干断层扫描和光学频域成像(OFDI)已被用于血管显微解剖的二维和三维成像。然而,由于冠状动脉内导管和血管壁之间的相对运动导致的伪影,多维重建的图像质量和空间精度可能会降低。为了跟踪导管相对于血管的相对运动,采用波分复用技术将运动跟踪系统与标准对外直接投资系统结合起来。通过多普勒效应引起的后向散射光的频移来获取血管的运动。利用单个单色光束跟踪基于导管的光纤探头相对于血管的相对纵向位移。虽然两个跟踪波束,在一般情况下,需要校正纵向运动伪影,在纵向视图中的准确重建是通过一个单一的波束的多普勒频率信息实现的。我们的研究结果表明,基于单波束的运动跟踪方案是一种具有成本效益的,实用的方法来补偿由于心脏动力学的纵向失真,从而导致准确的定量分析三维冠状动脉内对外直接投资。
Intracoronary optical coherence tomography and optical frequency domain imaging (OFDI) have been utilized for two-dimensional and three-dimensional imaging of vascular microanatomy. Image quality and the spatial accuracy of multidimensional reconstructions, however, can be degraded due to artifacts resulting from relative motion between the intracoronary catheter and the vessel wall. To track the relative motion of a catheter with regard to the vessel, a motion tracking system was incorporated with a standard OFDI system by using wavelength division multiplexing techniques. Motion of the vessel was acquired by a frequency shift of the backscattered light caused by the Doppler effect. A single monochromatic beam was utilized for tracking the relative longitudinal displacements of a catheter-based fiber probe with regard to the vessel. Although two tracking beams are, in general, required to correct for longitudinal motion artifacts, the accurate reconstruction in a longitudinal view was achieved by the Doppler frequency information of a single beam. Our results demonstrate that the single beam based motion tracking scheme is a cost-effective, practical approach to compensating for longitudinal distortions due to cardiac dynamics, thus leading to accurate quantitative analysis of 3D intracoronary OFDI.