Triterpenoids from Brazilian Ginseng, Pfaffia paniculata

Triterpenoids from Brazilian Ginseng, Pfaffia paniculata
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DOI:
10.1055/s-0029-1240631
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发表时间:
2010-04-01
期刊:
影响因子:
2.7
通讯作者:
Khan, Ikhlas A.
Khan, Ikhlas A.
中科院分区:
医学3区
文献类型:
--
作者:
Li, Jing;Jadhav, Atul N.;Khan, Ikhlas A.

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! Two new nortriterpenoids, pfaffine A and B (1-2), were isolated from the roots of Pfaffia paniculata Kuntze, along with ten known compounds including four ecdysteroids, ecdysone (3), 20-hydroxyecdysone (4), pterosterone (5), rapisterone (6), five triter-penoids, pfaffic acid (7), pfameric acid (8), mesembryanthemoidigenic acid (9), calenduloside E 6'-methyl ester (10), oleanolic acid 28-O-beta-D-glucopyranoside (11), and one monoterpene glycoside (+)-angelicoidenol-2-O--D-glucopyranoside (12). The structures of the new compounds were elucidated as 3 beta, 16 beta-dihydroxy-30-norolean-12,20(29)-dien-28-oic acid (1), and 3 beta-hydroxy30- norolean-12,20(29)-dien-28-oic acid-28-O-beta-D-glucoside (2) through the extensive analysis of 1D-((1)H, (13)C, DEPT) and 2D -NMR (COSY, HSQC, HMBC, NOESY) spectra, as well as by a chemical method. Downloaded by: Thomson Reuters. Copyrighted material.