Chiral β-Iodoamines by Urea-Catalyzed Iodocyclization of Trichloroacetimidates.
Chiral β-Iodoamines by Urea-Catalyzed Iodocyclization of Trichloroacetimidates.
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DOI：
10.1039/c3sc50410g
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发表时间：
2013-05-01
期刊：
影响因子：
--
通讯作者：
Jacobsen EN
中科院分区：
文献类型：
--
作者：
Brindle CS;Yeung CS;Jacobsen EN
烯烃的高度对映选择性邻碘胺化是通过一种新的手性希夫碱脲衍生物催化的三氯乙酸烯基酯的碘环化来完成的。所得产物很容易转化为各种含多功能胺的手性构建块。
Highly enantioselective vicinal iodoamination of olefins is accomplished through the iodocyclization of alkenyl trichloroacetimidates catalyzed by a new chiral Schiff-base urea derivative. The resulting products are converted readily to a variety of polyfunctional amine-containing chiral building blocks.