Inhibition of feline immunodeficiency virus (FIV) replication by DNA binding polyamides.
Inhibition of feline immunodeficiency virus (FIV) replication by DNA binding polyamides.
复制标题
通过 DNA 结合聚酰胺抑制猫免疫缺陷病毒 (FIV) 复制。
DOI：
10.1016/s0960-894x(02)00307-4
复制
发表时间：
2002
影响因子：
2.7
通讯作者：
Lown,JWilliam
中科院分区：
文献类型：
--
作者：
Sharma,SanjayK;Billaud,Jean-Noel;Tandon,Manju;Billet,Olivier;Choi,Sam;Kopka,MaryL;Phillips,TomR;Lown,JWilliam
Two DNA minor-groove binding polyamides 1 and 2 were designed and synthesized and evaluated for inhibition of FIV-34TF10 replication. Both 1 and 2 decreased the replication of FIV-34TF10 by 75% by acting at the level of the virus but outside of the LTR or env region.
