The morphology of the optic nerve head in the Singaporean Chinese population (the Tanjong Pagar study): part 1 - optic nerve head morphology

The morphology of the optic nerve head in the Singaporean Chinese population (the Tanjong Pagar study): part 1 - optic nerve head morphology
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DOI:
10.1136/bjo.2007.123273
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发表时间:
2008-03-01
影响因子:
4.1
通讯作者:
Garway-Heath, D. F.
Garway-Heath, D. F.
中科院分区:
医学2区
文献类型:
--
作者:
Bourne, R. R. A.;Foster, P. J.;Garway-Heath, D. F.

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背景/目的:研究中国人群视盘参数与人口学变量的相关性。方法:采用一种新的平面立体摄影方法,从新加坡Tanjong Pagar青光眼调查中获得929名年龄为40岁的受试者的视盘数据。生物测量学数据(屈光度、角膜曲率、眼轴长度、前房深度、晶状体厚度)用于计算眼球放大倍数。相机的放大率是用模型眼量化的。结果:视盘中位面积(DA)、视杯面积(CA)和眼缘面积(RA)分别为2.09(1.28-4.01)mm(2)、0.69(0.01-1.90)mm(2)和1.38(0.82-2.50)mm(2)。有强有力的证据表明DA和RA之间存在关联(Spearman‘s Rho 0.624,p
Background/aims: To investigate the correlation between optic disc parameters and their association with demographic variables in a Chinese population.Methods: Disc data were obtained from 929 subjects aged >= 40 years from the Tanjong Pagar glaucoma survey of Singapore, using a novel planimetric method of sequential stereo-photographs. Biometric data (refractive error, keratometry, axial length, anterior chamber depth, lens thickness) were used to calculate ocular magnification. Camera magnification was quantified with a model eye. A "normal'' dataset of 622 subjects was generated by exclusion of subjects with abnormal results on psychophysical testing, an occludable angle or an intraocular pressure >97.5th percentile in either eye.Results: Median disc area (DA), cup area (CA), and rim area (RA) were 2.09 (range 1.28-4.01) mm(2), 0.69 (0.01-1.90) mm(2) and 1.38 (0.82-2.50) mm(2), respectively. There was strong evidence of an association between DA and RA (Spearman's rho 0.624, p