On-chip magnetically actuated robot with ultrasonic vibration for single cell manipulations
On-chip magnetically actuated robot with ultrasonic vibration for single cell manipulations
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DOI：
10.1039/c1lc20164f
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发表时间：
2011-01-01
期刊：
影响因子：
6.1
通讯作者：
Arai, Fumihito
中科院分区：
文献类型：
--
作者：
Hagiwara, Masaya;Kawahara, Tomohiro;Arai, Fumihito
提出了一种基于微流控芯片的永磁驱动片上机器人的驱动方法。采用压电陶瓷对微流控芯片进行超声振动，高频振动显著降低了微流控芯片与蒙脱土之间的有效摩擦。因此，我们实现了1.1微米的微型机器人定位精度，这是100倍的精度比没有振动。响应速度也得到了提高，微机器人可以在3个自由度上以5.5 mm s（-1）的速度驱动。超声振动的新奇也体现在输出力上。与微型机器人上的摩擦减少相反，超声波振动的输出力增加了两倍。使用这种高精度，高速度，高功率的微型机器人，猪卵母细胞的操作在微流控芯片。
This paper presents an innovative driving method for an on-chip robot actuated by permanent magnets in a microfluidic chip. A piezoelectric ceramic is applied to induce ultrasonic vibration to the microfluidic chip and the high-frequency vibration reduces the effective friction on the MMT significantly. As a result, we achieved 1.1 micrometre positioning accuracy of the microrobot, which is 100 times higher accuracy than without vibration. The response speed is also improved and the microrobot can be actuated with a speed of 5.5 mm s(-1) in 3 degrees of freedom. The novelty of the ultrasonic vibration appears in the output force as well. Contrary to the reduction of friction on the microrobot, the output force increased twice as much by the ultrasonic vibration. Using this high accuracy, high speed, and high power microrobot, swine oocyte manipulations are presented in a microfluidic chip.