Response of Pacinian corpuscles to sinusoidal vibration
Response of Pacinian corpuscles to sinusoidal vibration
复制标题
帕西尼亚小体对正弦振动的响应
DOI：
10.1113/jphysiol.1961.sp006817
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发表时间：
1961
期刊：
影响因子：
--
通讯作者：
M. Sato
中科院分区：
文献类型：
--
作者：
M. Sato
到目前为止，关于Pacinian小体在体内的功能意义的信息很少。然而，由于它们的快速适应，它们必须不断受到身体最快速运动的刺激，例如心跳、呼吸和身体加速，它们对外部施加的振动也非常敏感（Gray和马修斯，1951 a）。最近，Hunt和McIntyre（1960）在猫后肢的骨间膜中发现了振动感受器，其快速适应，通常非常敏感，并对40至700 c/s的振动刺激作出反应，Hunt（1961）观察到了与Hunt & McIntyre（1960）描述的类似的振动感受器在这项研究中，他将这些受体鉴定为Pacinian小体。因此，需要更详细地研究帕西尼小体对正弦振动的反应，并将其结果与Hunt & McIntyre（1960）和Hunt（1961）的实验以及人类受试者的实验（Geldard，1940）进行比较。虽然过去已经用猫肠系膜和其他部位的帕西尼小体进行了许多实验，但只有少数实验涉及正弦机械刺激对小体的刺激（Scott，1951; Loewenstein，1958）。然而，这些似乎没有提供关于这个问题的很多信息。因此，本文将描述的实验中确定的阈值肠系膜小体，无论是从猫或未解剖和完整的循环，以各种频率的正弦振动。还研究了来自小体内的无髓鞘末梢的响应于振动的受体电位（Gray & Sato，1953）。
There has so far been little information regarding the functional significance of Pacinian corpuscles in the body. However, because of their rapid adaptation they must be constantly stimulated by most quick movements of the body, e.g. by heartbeat, respiration and acceleration of the body, and they are also very sensitive to externally applied vibration (Gray & Matthews, 1951a). Recently Hunt & McIntyre (1960) have found vibration receptors, which are rapidly adapting, often extremely sensitive and responding to vibratory stimuli between 40 and 700 c/s, in the interosseous membrane of the hind limbs of the cat, and Hunt (1961) has observed similar vibration receptors to those described by Hunt & McIntyre (1960) in close association with the tibial periosteum of the cat. In this study he identified these receptors as Pacinian corpuscles. It is therefore desirable to investigate the response of Pacinian corpuscles to sinusoidal vibration in more detail, and to compare its results with the experiments of Hunt & McIntyre (1960) and Hunt (1961), and also with those on human subjects (Geldard, 1940). Although in the past many experiments have been carried out with Pacinian corpuscles in the mesentery and in other parts of the cat, there have been only a few experiments dealing with the stimulation of corpuscles by sinusoidal mechanical stimuli (Scott, 1951; Loewenstein, 1958). These, however, do not seem to give much information on this subject. This paper will therefore describe experiments in which the threshold was determined of the mesenteric corpuscle, either isolated from the cat or undissected and with intact circulation, to sinusoidal vibrations of various frequencies. The receptor potential from the non-myelinated ending inside the corpuscle (Gray & Sato, 1953) in response to vibrations has also been investigated.