Capillary affinity gel electrophoresis

Capillary affinity gel electrophoresis
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毛细管亲和凝胶电泳

DOI:
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发表时间:
1996
期刊:
影响因子:
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通讯作者:
Y. Baba
Y. Baba
中科院分区:
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文献类型:
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作者:
Y. Baba

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毛细管亲和凝胶电泳法是一种识别特定DNA碱基和/或序列的新技术。这项技术也适用于DNA药物结合特性的表征、手性分离以及利用印迹聚合物选择性分离抗体模拟物。本文综述了毛细管亲和凝胶电泳法的研究现状,包括该技术的原理、原理、方法和应用。说明了毛细管亲和凝胶电泳法在DNA突变检测中的巨大潜力。
Capillary affinity gel electrophoresis is a new technique for the recognition of the specific DNA base and/or sequence. This technology is also applicable to the characterization of binding properties of DNA-based drugs, chiral separation, and the selective separation of antibody mimetics using imprinted polymers. This article reviews the present state of studies on the capillary affinity gel electrophoresis, including the principle, theory, methods, and applications of this technology. The great potential of capillary affinity gel electrophoresis for the detection of the mutation onDNA is illustrated.