Degeneration of retinal neuronal processes and pigment epithelium in the early stage of the streptozotocin-diabetic rats
Degeneration of retinal neuronal processes and pigment epithelium in the early stage of the streptozotocin-diabetic rats
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DOI：
10.1046/j.1440-1789.2002.00439.x
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发表时间：
2002-09-01
期刊：
影响因子：
2.3
通讯作者：
Nakagawa, H
中科院分区：
文献类型：
--
作者：
Aizu, Y;Oyanagi, K;Nakagawa, H
用光镜、电镜和视网膜电图观察了链脲佐菌素（STZ）糖尿病大鼠早期视网膜的病理和电生理变化。SD大鼠糖尿病发病后1个月，视网膜内网状层（IPL）和感光节层（PSL）厚度分别减少9.9%和18.9%（P
Early pathological and electro-physiological changes of the retina in the streptozotocin (STZ)-diabetic rats were investigated through optical and electron microscopy in two strains and electro-retinography in one strain. In Sprague-Dawley (SD) rats 1 month after the onset of diabetes, the thickness of the inner plexiform layer (IPL) and photoreceptor segment layer (PSL) was significantly reduced by 9.9% and 18.9%, respectively (P